2026-10-12T12:33:22Z https://api.figshare.com/v2/oai

oai:figshare.com:article/30576644 2026-10-01T16:34:33Z category_24256 item_type_3 month_year_10_2026

Genetic adaptation to polyploidy in animals: a case study in Australian burrowing frogs Neobatrachus Jie Wang (22588046) Evolutionary ecology polyploidy frog adaptation evolution <p dir="ltr"><b>Whole-genome duplication can be adaptive in the long term but in the short term can impair chromosome segregation and fertility, obstacles polyploids must overcome to regain fitness. To investigate how animals adapt to polyploidy, we focused on Australian burrowing frogs (genus Neobatrachus), three species of which are polyploid: </b><b><i>N. aquilonius</i></b><b>, </b><b><i>N. kunapalari </i></b><b>and </b><b><i>N. sudellae</i></b><b>. We assembled a reference genome for diploid </b><b><i>N. pictus</i></b><b> and sequenced 96 individuals from all nine </b><b><i>Neobatrachus </i></b><b>species, finding tetraploid-specific selection on genes with meiotic roles in synaptonemal complex and crossover distribution (SYCE2, PRR19), or chromosome and spindle size (Condensin-2, KifC1). These changes may represent a genetic adaptation in vertebrate polyploids with tetrasomic and mixed inheritance that raises crossover interference and scales chromosome and spindle size to ensure successful chromosomal segregation. Finally, we show that adaptive alleles are shared between the tetraploids via interspecific introgression. </b></p> 2025-11-11T17:18:00Z Dataset Dataset 10.6084/m9.figshare.30576644.v10 https://figshare.com/articles/dataset/Changes_in_cell_cycle_machinery_as_genetic_basis_for_polyploidy_stabilization_in_Australian_burrowing_frogs_Neobatrachus_/30576644 CC BY 4.0