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oai:figshare.com:article/30425002 2025-08-01T00:00:00Z portal_693 item_type_8 month_year_08_2025

Molar Incisor Hypomineralization and Developmental Dental Anomalies: A Case-Control Study Juno Park (22481752) Health Sciences Dentistry Title: Molar Incisor Hypomineralization and Dental Anomalies: A Case-Control Study Authors : Park J1, Kratunova E1, Alrayyes S1, Alsaleh M1,Galang-Boquiren M2, Ahmed AT 1 Author affiliations :1 Department of Pediatric Dentistry, College of Dentistry, University of Illinois, Chicago, IL, USA Objectives: To evaluate the association between Molar Incisor Hypomineralization (MIH), early-life adverse environmental and medical events, and co-existing developmental dental anomalies (DDA). Methods: This case-control study included children aged 6–13 years, with the presence of MIH serving as the inclusion criterion for the case group. Each child with MIH was matched with a child without MIH of similar age and demographic characteristics to form the control group. Trained and calibrated examiners assessed MIH using standardized diagnostic criteria. Biological mothers completed a structured questionnaire addressing pregnancy and early-life adverse events. DDA were identified through clinical and radiographic assessment. Statistical analyses included descriptive statistics, Chi-square and Fisher’s exact tests, and logistic regression. Results: A total of 56 children were enrolled, including 28 in the MIH group and 28 in the control group. The mean age was 9.32 ± 1.89 years in the MIH group and 8.24 ± 1.46 years in the control group. Among the MIH group, 89.3% were born in the United States compared to 96.3% in the control group, and 70.4% were Hispanic or Latino compared to 78.6% in the control group. Developmental dental anomalies were significantly associated with MIH (χ² = 6.76, P = .0093). No significant differences were found in pregnancy, environmental and early-life adverse events between the MIH and control groups (P > .05). Conclusions: This preliminary study demonstrates a significant association between MIH and the presence of DDA. Further research with larger sample sizes is needed to confirm these findings. 2025-08-01T00:00:00Z Text Thesis 10.25417/uic.30425002.v1 https://figshare.com/articles/thesis/Molar_Incisor_Hypomineralization_and_Developmental_Dental_Anomalies_A_Case-Control_Study/30425002 In Copyright