2026-10-15T11:46:41Z https://api.figshare.com/v2/oai

oai:figshare.com:article/29719403 2025-10-01T14:27:29Z category_27235 portal_753 item_type_3 month_year_10_2025

Development of a functional acellular dermal scaffold (ADS) using 3D bioprinting to address challenges in secondary intent wound care Princess Ijeoma (21846629) Traditional, complementary and integrative medicine not elsewhere classified Bioprinting methods 3D imaging techniques Wound healing application multifunctional hydrogel Micro-XCT scanning Wound healing Acellular dermal scaffold (ADS) SDG 3 Good health and wellbeing <p dir="ltr">This research explored the world of Micro-XCT imaging to produce an intact and structurally sound scaffold STL file created from a porcine biopsy. This was then bioprinted using a combination of a collagen hydrogel and a mixture of fibroblast cells and showed a preservation of the fibroblast cells. a digital pipeline was employed to reconstruct a 3D printable model of an ADS scaffold from micro-XCT scans of porcine dermis scaffold samples. This approach allowed for the accurate translation of natural ECM structures into a digital format, enabling a consistent scaffold design. Three porcine samples were scanned, digitally processed, and converted into 3D models suitable for bioprinting. The models were bioprinted using collagen mixed with primary human dermal fibroblast cells (PHDFs).</p> 2025-10-01T14:27:29Z Dataset Dataset 10.25403/UPresearchdata.29719403.v1 https://figshare.com/articles/dataset/Development_of_a_functional_acellular_dermal_scaffold_ADS_using_3D_bioprinting_to_address_challenges_in_secondary_intent_wound_care/29719403 CC BY 4.0