2026-10-15T14:51:31Z https://api.figshare.com/v2/oai

oai:figshare.com:article/29256509 2025-06-11T11:33:08Z category_24178 portal_918 item_type_3 month_year_06_2025

Figure 3E Raw data - <b>Increased </b><b><i>in vivo</i></b><b> transduction of AAV-9 cargo in Alport podocytes</b> Maryline Fresquet (21018995) Emily Williams (11461711) gema bolas (21211210) Rachel Lennon (8928569) Biochemistry and cell biology not elsewhere classified Figure 3D Raw data <p dir="ltr">Raw dataset and analysis for Figure 3E:</p><p dir="ltr"><br></p><p dir="ltr"><b>Figure 3: AAV9-GFP transduction in kidneys of wild type and Alport mice injected at low (6.6x10</b>^{<strong>12</strong>}<b> vg/kg), medium (3.3x10</b>^{<strong>13</strong>}<b> vg/kg) and high (1.65x10</b>^{<strong>14</strong>}<b> vg/kg) dose. </b>In total, 6 (3 WT and 3 Col4a5 KO) 8-week-old mice per group were injected with either AAV9-GFP or saline. <b>E)</b> Colocalization for WT1 and GFP signals was quantified using QuPath and plotted as the percentage of GFP-positive podocytes. The entirety of glomeruli from 2 whole kidney cross-sections (per genotype/condition) were quantified. Data are presented as mean ± SEM of the values from 3 mice per group and per genotype. P value<0.05 (*), <0.005 (**), <0.0005 (***).</p> 2025-06-11T11:33:08Z Dataset Dataset 10.48420/29256509.v1 https://figshare.com/articles/dataset/Figure_3E_Raw_data_-_b_Increased_b_b_i_in_vivo_i_b_b_transduction_of_AAV-9_cargo_in_Alport_podocytes_b_/29256509 CC0