2026-05-07T05:58:40Z https://api.figshare.com/v2/oai
oai:figshare.com:article/22940153 2023-11-19T00:10:06Z category_24892 portal_549 item_type_3 month_year_11_2023
10.5522/04/22940153.v1 https://figshare.com/articles/dataset/Primary_human_Hepatic_Stellate_Cells_and_PNPLA3_I148M/22940153 https://ndownloader.figshare.com/files/40700801 10.1136/gutjnl-2019-319226 Rombouts, Krista Krista Rombouts Caon, Elisabetta Elisabetta Caon <![CDATA[Primary human Hepatic Stellate Cells and PNPLA3 I148M]]> Other biomedical and clinical sciences not elsewhere classified RNA sequencing results NanoString nCounter analysis primary human Hepatic Stellate Cells (HSC) human liver ECM scaffolds pnpla3 i148m variant genotyping TGFB1 Nr4a1 (Nur77) oxidative stress 2023-05-22 2023-11-19 Dataset 2023 University College London  A) RNA sequencing was performed on 2D-cultured primary human Hepatic Stellate Cells (HSC) genotyped for the PNPLA3 I148M variant. 

B) RNA sequencing from liver biopsies of genotyped PNPLA3 patients, previously published (http:// dx. doi. org/ 10. 1136/gutjnl- 2019- 319226).

C) Comparison of both datasets of A and B.

D) Cell behaviour was evaluated in HSCs wild type (WT) or carrying I148M PNPLA3 cultured on 3D extracellular matrix (ECM) scaffolds from human healthy and cirrhotic liver with/without TGFB1 and NanoString was employed.  

All datasets are available in Excel files.

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