2026-06-01T16:42:25Z https://api.figshare.com/v2/oai
oai:figshare.com:article/19650942 2022-04-25T15:25:13Z category_24748 portal_549 item_type_3 month_year_04_2022
10.5522/04/19650942.v1 https://figshare.com/articles/dataset/Extracellular_spinal_recordings_spontaneous_activity_and_fictive_locomotion/19650942 https://ndownloader.figshare.com/files/39704161 https://ndownloader.figshare.com/files/39704158 Pocratsky, Amanda Amanda Pocratsky Do Nascimento Xavier Fernandes, Filipe Filipe Do Nascimento Xavier Fernandes Ozyurt, Gorkem Gorkem Ozyurt White, Ian Ian White Sullivan, Roisin Roisin Sullivan O'Callaghan, Benjamin Benjamin O'Callaghan Smith, Calvin Calvin Smith Surana, Sunaina Sunaina Surana Beato, Marco Marco Beato Brownstone, Rob Rob Brownstone <![CDATA[Extracellular spinal recordings: spontaneous activity and fictive locomotion]]> Neurosciences not elsewhere classified movement disorder dystonia spinal cord fictive locomotion Neuroscience DYT1 2023-03-27 2023-03-27 Dataset 2022 University College London In vitro extracellular recording dataset of spontaneous activity in normal artificial cerebrospinal fluid (aCSF) and drug-induced fictive locomotion associated with Pocratsky et al 2023, Science Translational Medicine


ENG_spontAct_aCSF.xlsx: raw and analysed data from extracellular recordings from lumbar spinal ventral roots of postnatal spinal cords (postnataly day 3-5). Data reflects spontaneous activity observed when cords were perfused with artifical cerebrospinal fluid (aCSF). Groups: Littermate control and spinal Tor1a d-cko mice that develop early onset generalised torsional dystonia


ENG_fictiveLocomotion.xlsx: raw and analysed data from extracellular recordings from lumbar spinal ventral roots of postnatal spinal cords (postnatal day 1-5). Data reflects stable rhythmic bursting activity observed when cords were perfused with aCSF mixed with a cocktail of NMDA, 5-HT, and dopamine (for p3-p5 recordings, only). 


Full methodological details can be found with publication



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