2026-07-30T20:36:25Z https://api.figshare.com/v2/oai
oai:figshare.com:article/14482977 2021-08-23T15:50:12Z category_24748 portal_549 item_type_3 month_year_08_2021
10.5522/04/14482977.v1 https://figshare.com/articles/dataset/Cerebellar_granule_cell_axons_support_high_dimensional_representations/14482977 10.1038/s41593-021-00873-x Lanore, Frederic Frederic Lanore 0000-0003-4316-6855 Silver, Angus Angus Silver 0000-0002-5480-6638 Cayco Gajic, None Cayco Gajic <![CDATA[Cerebellar granule cell axons support high dimensional representations]]> Neurosciences not elsewhere classified cerebellum parallel fibres system neuroscience population coding AOL microscope calcium imaging Neuroscience 2021-08-23 2023-06-01 Dataset 2021 University College London This page provides the links to the raw data and analysis scripts for the figures in the following publication:

Lanore, F., Cayco-Gajic, N.A., Gurnani, H., Coyle, C., Silver, R.A. (2021). Cerebellar granule cell axons support high dimensional representations. Nature Neuroscience 24(8):1142-1150. doi: 10.1038/s41593-021-00873-x

In this study we used Acousto-Optic Lens (AOL) 3D two-photon microscopy to image large populations of granule cell axons (parallel fibres) in the cerebellar cortex of spontaneously behaving mice. We examined how different behavioral states and sensorimotor variables are represented in granule cell population activity. We characterized the manifold structure of the coding subspace and estimated dimensionality of the representations.

Main project page:

https://figshare.com/projects/Cerebellar_granule_cell_axons_support_high_dimensional_representations/101456

The fibre direction data is here:

https://figshare.com/articles/dataset/Fibre_Direction_Data/14976822

Functional data after grouping is here:

https://figshare.com/articles/dataset/Functional_Data/14976891

The Metadata is here:

https://figshare.com/articles/dataset/Metadata_Files/14976837
The code used for data processing and analysis can be found on

GitHub here:

https://github.com/SilverLabUCL/ParallelFibres

Please cite the paper if you use this code in your research. For any questions, contact Alex Cayco-Gajic (natasha.cayco.gajic@ens.fr) or Angus Silver (a.silver@ucl.ac.uk).
]]>