2026-05-05T22:12:47Z https://api.figshare.com/v2/oai
oai:figshare.com:article/11396565 2020-01-29T15:09:27Z category_24319 portal_549 item_type_3 month_year_01_2020
10.5522/04/11396565.v1 https://figshare.com/articles/dataset/Two-cohort_Cambridge_and_EUGENDA_GWAS_meta-analyses_of_FHR-4_and_FH_levels/11396565 https://ndownloader.figshare.com/files/21003873 https://ndownloader.figshare.com/files/21003879 https://ndownloader.figshare.com/files/21003885 https://ndownloader.figshare.com/files/21003894 https://ndownloader.figshare.com/files/21445788 Cipriani, Valentina Valentina Cipriani Lorés-Motta, Laura Laura Lorés-Motta <![CDATA[Two-cohort (Cambridge and EUGENDA) GWAS meta-analyses of FHR-4 and FH levels]]> Genetics not elsewhere classified Macular degeneration factor H levels Factor H-Related Protein 4 levels GWAS Genetics 2020-02-07 2020-02-07 Dataset 2020 University College London The data repository consists of four files of summary statistics from the two-cohort (Cambridge and EUGENDA) GWAS meta-analyses of FH and FHR-4 levels:


METAANALYSIS_FH_ALL-adjAMD.txt (tab-separated values file; size: 448Mb)

METAANALYSIS_FH_controls.txt (tab-separated values file; size: 448Mb)

METAANALYSIS_FHR4_ALL-adjAMD.txt (tab-separated values file; size: 432Mb)

METAANALYSIS_FHR4_controls.txt (tab-separated values file; size: 432Mb)


The single-cohort GWASs were carried out using EPACTS software available at http://genome.sph.umich.edu/wiki/EPACTS; effect size estimates and standard errors of single variants seen in both cohorts were subsequently combined in a fixed-effect meta-analysis using METAL software available at http://csg.sph.umich.edu/abecasis/metal/download/.


More details are provided in the Readme.pdf file.

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